Viral Pathogens Detection Kits
RevoDx Human parechovirus qPCR Kit
Human parechoviruses (HPeV) are responsible for gastrointestinal and respiratory system infections. that also have recently been recognized to cause a variety of symptoms ranging from mild diarrhea to sepsis and meningitis, particularly among young children. HPeVs belong to a large family of nonenveloped, positive-sense, single-stranded RNA viruses, the Picornaviridae, which comprises 12 genera. Rarely, parechovirus can cause sepsis, a severe blood infection, or meningitis or encephalitis, a severe infection of the membrane surrounding the brain. These are most common in babies younger than 3 months. Symptoms to look out for in babies and young children include: fever. irritability.
Intended Use
RevoDx Human parechovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of HPEVs RNA.
RevoDx Enterovirus/Rhinovirus qPCR Kit
Human enteroviruses (HEVs) and human rhinoviruses (HRVs) are the two viruses that infect individuals most frequently globally.Rhinoviruses (RVs) and respiratory enteroviruses (EVs) are leading causes of upper respiratory tract infections, acute asthma exacerbations, bronchiolitis, viral pneumonia and among the most frequent infectious agents in humans worldwide. Both are classified in the Enterovirus genus within the Picornaviridae family. They can also be spread by contact – either with the infected person (like kissing or shaking hands), or by touching contaminated surfaces and then touching your mouth, nose, or eyes. These viruses can survive on surfaces for many hours. Symptoms usually include: sore throat, cough and nasal congestion, wheezing and dyspnea, to hospitalization requiring supplemental oxygen, or much less commonly lead to fulminant respiratory failure requiring mechanical ventilation.
Intended Use
RevoDx Enterovirus/Rhinovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Enterovirus and Rhinovirus RNA.
RevoDx Mumps Virus qPCR Kit
Mumps is a contagious disease caused by a virus mumps virus that is an RNA virus in the family Paramyxoviridae. The virus is primarily transmitted by respiratory secretions such as droplets and saliva, as well as via direct contact with an infected person. It typically starts with a few days of fever, headache, muscle aches, tiredness, and loss of appetite. Then most people will have swelling of their salivary glands (often referred to as parotitis when the parotid gland, located in front and below the ear, swells). This is what causes the puffy cheeks and a tender, swollen jaw. Mumps is most recognizable by the painful swellings in the side of the face under the ears (the parotid glands), giving a person with mumps a distinctive “hamster face” appearance.
Intended Use
RevoDx Mumps Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of Mumps Virus RNA.
RevoDx African Swine Fever Virus qPCR Kit
African swine fever (ASF) is a devastating hemorrhagic swine fever with high morbidity and mortality caused by African swine fever virus (ASFV), a large double-stranded DNA virus. The ASFV genome is a virus that ranges in size from 170 to 193 kbp among different isolates and contains between 150 and 167 open reading frames (ORFs). ASFV has various genotypes, a large number of coding proteins, and forms a complex structure. Therefore, it has escape mechanisms from host immune cells. Pigs are infected by virus-carrying ticks and other ticks in their bodies become infected by pigs with high viremia. This allows the epidemic to spread among other pigs. The ASFV virion is highly stable in vitro and provides favorable conditions for direct pig-to-swine transmission. The virus can be easily transmitted through contaminated pork products and mixed feed.
Intended Use
RevoDx African Swine Fever Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of ASFV DNA.
RevoDx BK Virus qPCR Kit
BK virus (BKV) was originally discovered and isolated from the urine of a renal allograft recipient. The source of BKV infection is due to decline in immunologic activity from either graft dysfunction and graft rejection in renal transplant recipients under immunosuppressed state. Detection of BKV has traditionally relied on tissue examination, but PCR is the best diagnostic test for use in human samples since it provides fast and accurate results and is highly sensitive and specific for quantification of BKV DNA.
Intended Use
RevoDx BK Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of BK virus DNA.
RevoDx JC Virus qPCR Kit
JCV is a DNA virus belonging to the polyomavirus family. Studies on serum samples have shown that people typically experience asymptomatic primary infection with JCV during childhood, usually before the age of 5. By the time individuals reach adulthood, approximately 85% of the population has antibodies indicating past exposure to the virus. After the initial infection, JCV enters a latent phase in various parts of the body, including the kidney, bone marrow, and tonsils. It remains uncertain whether the virus also enters a latent state in the central nervous system (CNS). In immunocompetent individuals, JCV reactivation often occurs without symptoms, manifesting as asymptomatic viruria.
Intended Use
RevoDx JC Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of JC virus DNA.
RevoDx BK / JC Virus Screening qPCR Kit
BK virus (BKV) was originally discovered and isolated from the urine of a renal allograft recipient. The source of BKV infection is due to decline in immunologic activity from either graft dysfunction and graft rejection in renal transplant recipients under immunosuppressed state. JCV is a DNA virus belonging to the polyomavirus family. Studies on serum samples have shown that people typically experience asymptomatic primary infection with JCV during childhood, usually before the age of 5. By the time individuals reach adulthood, approximately 85% of the population has antibodies indicating past exposure to the virus. After the initial infection, JCV enters a latent phase in various parts of the body, including the kidney, bone marrow, and tonsils.
Intended Use
RevoDx BK / JC Virus Screening qPCR Kit is a real-time PCR test intended for the qualitative detection of BK and JC virus DNA.
RevoDx BK / JC Virus qPCR Kit
Polyomaviruses are a family of widespread and species-specific viruses classified under the Papovaviridae family. The two most prevalent polyomaviruses in humans, BK virus and JC virus, were first identified in the 1970s. Many individuals encounter these viruses during childhood, resulting in mild illnesses. However, in immunocompromised individuals, these viruses, when reactivated or acquired, have been linked to various clinical conditions. BK virus is commonly associated with renal issues such as ureteral stenosis, hemorrhagic cystitis, and nephropathy. It can also, although less frequently, lead to conditions like pneumonitis, retinitis, liver disease, and meningoencephalitis. JC virus is best known for its connection to progressive multifocal leukoencephalopathy and is possibly involved in the development of different human tumors.
Intended Use
RevoDx BK/JC Virus qPCR Kit is a real-time PCR test intended for the qualitative detection and identification of BK/JC Virus DNA.
RevoDx Parvovirus B19 Qualitative qPCR Kit
Adenoviruses (AdV) are a type of DNA virus that commonly cause mild infections in the upper or lower respiratory tract, gastrointestinal (GI) tract, or eyes. In rare cases, AdV infections can lead to more serious conditions such as hemorrhagic cystitis, hepatitis, hemorrhagic colitis, pancreatitis, nephritis, or encephalitis. Young children are more susceptible to AdV infections due to their underdeveloped immune systems. Epidemics of AdV infections can occur in closed or crowded environments, especially among military recruits. The disease can be more severe and likely to spread in individuals with weakened immune systems, such as organ transplant recipients, people with HIV/AIDS, or those with congenital immunodeficiency syndromes.
Intended Use
RevoDx Adenovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Adenovirus DNA.
RevoDx Adenovirus qPCR Kit
Human enteroviruses (HEVs) and human rhinoviruses (HRVs) are the two viruses that infect individuals most frequently globally.Rhinoviruses (RVs) and respiratory enteroviruses (EVs) are leading causes of upper respiratory tract infections, acute asthma exacerbations, bronchiolitis, viral pneumonia and among the most frequent infectious agents in humans worldwide. Both are classified in the Enterovirus genus within the Picornaviridae family. They can also be spread by contact – either with the infected person (like kissing or shaking hands), or by touching contaminated surfaces and then touching your mouth, nose, or eyes. These viruses can survive on surfaces for many hours. Symptoms usually include: sore throat, cough and nasal congestion, wheezing and dyspnea, to hospitalization requiring supplemental oxygen, or much less commonly lead to fulminant respiratory failure requiring mechanical ventilation.
Intended Use
RevoDx Enterovirus/Rhinovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Enterovirus and Rhinovirus RNA.
RevoDx Bocavirus 1/2/3/4 qPCR Kit
Human Bocavirus (HBoV) includes types 1, 2, 3, and 4 belonging to the Bocaparvovirus genus. HBoV, a non-enveloped DNA virus Discovered in the early 2000s, these viruses are leading respiratory pathogens, especially affecting children. HBoV infections, often associated with respiratory symptoms such as cough and fever, exhibit a seasonal pattern and are common worldwide. Transmission occurs through respiratory droplets, which have higher susceptibility in crowded environments. While infections can affect all age groups, severe cases are more common in infants and people with pre-existing respiratory conditions. Ongoing research aims to elucidate the pathogenesis of the virus, its time course of spread, and potential interactions with other respiratory pathogens.
Intended Use
RevoDx Bocavirüs 1/2/3/4 qPCR Kit is a real-time PCR test intended for the qualitative detection of Bocavirus DNA.
RevoDx Metapneumovirus qPCR Kit
First identified in 2001, the human metapneumovirus (MPV) is a single-stranded RNA virus that is enclosed. By the age of five, almost all children have contracted the virus, but reinfection can happen at any time during life, particularly in elderly and immunocompromised individuals. Human Metapneumovirus is an important cause of bronchiolitis and pneumonia in children.
Intended Use
RevoDx Metapneumovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Metapneumovirus RNA.
RevoDx Coronavirus 229E/NL63/OC43/HKU1 qPCR Kit
Human coronaviruses (HCoVs) are RNA viruses. Coronaviruses are characterized by their large, positive-sense, single-stranded RNA genomes. The four species of human coronaviruses (HCoVs) include HKU1, NL63, 229E, and OC43. They are linked to a broad range of clinical manifestations. While HCoVs usually result in moderate upper respiratory tract infections in generally healthy children, they can sometimes cause severe lower respiratory tract infections, including pneumonia and bronchiolitis, in preterm newborns and children with persistent underlying illnesses.
Intended Use
RevoDx Coronavirus 229E/NL63/OC43/HKU1 qPCR Kit is a real-time PCR test intended for the qualitative detection of Coronavirus 229E/NL63/OC43/HKU1 RNA.
RevoDx Langya Virus qPCR Kit
Langya henipavirus is a newly identified virus that’s been diagnosed in 35 people in recent years. Healthcare providers diagnosed it during routine testing in China. It causes mild, flu-like symptoms like fever, cough and fatigue. Related viruses cause serious illness, so providers are monitoring it closely. No one has died from Langya virus.
Intended Use
RevoDx Langya qPCR Kit is a real-time PCR test intended for the qualitative detection of Lnagya virüs RNA.
RevoDx Parvovirus B19 Quantitative qPCR Kit
Human parvovirus B19 (B19V) is a small, single-stranded DNA virus that belongs to the Parvoviridae family. It primarily infects humans and is known to cause several clinical manifestations, including fifth disease (erythema infectiosum), arthritis, hydrops fetalis, and aplastic crisis, particularly in individuals with underlying hematologic disorders or compromised immune systems.
Polymerase chain reaction (PCR) assays can detect viral DNA in clinical specimens such as blood, serum, or respiratory secretions. PCR is highly sensitive and specific and can be particularly useful for diagnosing acute infections, especially in cases where serological tests may yield false-negative results.
Intended Use
RevoDx Parvovirus B19 Quantitative qPCR Kit is a real-time PCR test intended for the quantitative detection of Parvovirus B19 virus DNA.
RevoDx Rubella Virus qPCR Kit
Rubella virus, also known as German measles virus, is the causative agent of rubella, a contagious viral infection. Rubella virus is a single-stranded RNA virus of the genus Rubivirus, belonging to the family Togaviridae. Its genome is approximately 9,762 nucleotides long and encodes for structural and non-structural proteins.
Rubella virus is primarily transmitted through respiratory droplets when an infected person coughs or sneezes. In pregnant women, the virus can be transmitted to the fetus via the placenta, leading to congenital rubella syndrome (CRS). Early diagnosis, appropriate management, and public health measures are essential components of rubella control and prevention efforts.
Intended Use
RevoDx Rubella Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of Rubella virus RNA.
RevoDx Parainfluemza Virus 1 qPCR Kit
Parainfluenza virus 1 (PIV-1) is one of the human parainfluenza viruses that can cause respiratory tract infections. The virus has a helical nucleocapsid and an envelope with two main surface glycoproteins: hemagglutinin-neuraminidase (HN) and fusion (F) protein, which are crucial for viral attachment and entry into host cells. PIV-1 is a common cause of respiratory infections worldwide, particularly in young children. PIV-1 is a leading cause of croup in children, characterized by a “barking” cough, hoarseness, and stridor (a high-pitched wheezing sound caused by disrupted airflow). Timely diagnosis is crucial for appropriate management, especially in severe cases and in high-risk patient populations.
Intended Use
RevoDx Parainfluenza Virus 1 qPCR Kit is a real-time PCR test intended for the qualitative detection of Parainfluenza virus RNA.
RevoDx Parainfluemza Virus 2 qPCR Kit
Human Parainfluenza Virus 2 (PIV-2) belongs to the genus Rubulavirus within the family Paramyxoviridae. It is an enveloped, single-stranded, negative-sense RNA virus. PIV-2 is a common cause of respiratory infections, particularly in children, and can lead to significant illnesses such as croup. Accurate diagnosis, primarily through PCR, and supportive care are essential for managing PIV-2 infections.
Intended Use
RevoDx Parainfluenza Virus 2 qPCR Kit is a real-time PCR test intended for the qualitative detection of Parainfluenza virus 2 RNA.
RevoDx Parainfluemza Virus 3 qPCR Kit
Human Parainfluenza Virus 3 (HPIV-3) is a significant cause of respiratory infections, particularly in young children, leading to conditions such as bronchiolitis and pneumonia. Accurate diagnosis of Human Parainfluenza Virus 3 (PIV-3) infections is crucial for several reasons, impacting patient management, public health, and healthcare systems. Differentiating PIV-3 from other respiratory pathogens (such as Respiratory Syncytial Virus, influenza, adenoviruses) and conditions (such as bacterial pneumonia) ensures accurate diagnosis and appropriate treatment.
Intended Use
RevoDx Parainfluenza Virus 3 qPCR Kit is a real-time PCR test intended for the qualitative detection of Parainfluenza virus 3 RNA.
RevoDx Parainfluemza Virus 4 qPCR Kit
Human Parainfluenza Virus 4 (PIV-4) is one of the lesser-studied members of the human parainfluenza virus family, but it still plays a significant role in causing respiratory tract infections. PIV-4 is an enveloped virus with a single-stranded, negative-sense RNA genome. PIV-4 is less common than PIV-1, PIV-2, and PIV-3, but it is still an important cause of respiratory illness. The virus spreads via respiratory droplets from coughing or sneezing, direct contact with infected secretions, or contact with contaminated surfaces. Accurate diagnosis helps guide supportive treatment and avoids unnecessary use of antibiotics.
Intended Use
RevoDx Parainfluenza Virus 4 qPCR Kit is a real-time PCR test intended for the qualitative detection of Parainfluenza virus 4 RNA.
RevoDx Measles morbilivirus qPCR Kit
Measles virus causes a disease with seemingly innocent symptoms, such as fever and rash. However, measles immune suppression causes increased susceptibility to opportunistic infections that are responsible for the majority of over 100 000 yearly fatalities. The pathogenesis of measles is complex, because measles virus uses multiple receptors to infect different cell types in different phases of the disease.
Intended Use
RevoDx Measles morbilivirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Measles morbilivirus RNA.
RevoDx Sapovirus (I, II, IV, V) qPCR Kit
Sapovirus is a genus within the Caliciviridae family that is distributed globally. It is associated with self-limiting, sporadic, watery diarrhea that is typically milder than that associated with rotaviruses. Diagnosis of sapovirus diarrhea relies on laboratory testing, with reverse-transcriptase polymerase chain reaction (RT-PCR) being the current gold standard. Exposure occurs early in life, with most children exposed by the age of two years. There is no specific treatment or vaccine to combat sapovirus infection or disease, and treatment relies on maintaining fluid balance.
Intended Use
RevoDx Sapovirus (I, II, IV, V) qPCR Kit is a real-time PCR test intended for the qualitative detection of Sapovirus (I, II, IV, V) RNA.
RevoDx Norovirus genegroup I&II qPCR Kit
Noroviruses are a very diverse group of viruses that infect different mammalian species. In humans, norovirus is a major cause of acute gastroenteritis. Multiple norovirus infections can occur in a lifetime as the result of limited duration of acquired immunity and cross-protection among different strains. A combination of advances in sequencing methods and improvements on surveillance has provided new insights into norovirus diversification and emergence.
Intended Use
RevoDx Norovirus genogroup I&II qPCR Kit is a real-time PCR test intended for the qualitative detection of Norovirus genogroup I&II RNA.
RevoDx Rotavirus A qPCR Kit
Rotavirus is a very contagious virus that causes diarrhea. Before the development of a vaccine, most children had been infected with the virus at least once by age 5. Although rotavirus infections are unpleasant, you can usually treat this infection at home with extra fluids to prevent dehydration. Occasionally, severe dehydration requires receiving fluids through a vein (intravenously) in the hospital. Good hygiene, such as washing your hands regularly, is important. But vaccination is the best way to prevent rotavirus infection.
Intended Use
RevoDx Rotavirus A qPCR Kit is a real-time PCR test intended for the qualitative detection of Rotavirus A RNA.
RevoDx Adenovirus (F40/41) qPCR Kit
Human adenovirus (HAdV) types F40/41 have long been recognized as major viral agents of acute gastroenteritis (AGE) in children.
Intended Use
RevoDx Adenovirus (F40/41) qPCR Kit is a real-time PCR test intended for the qualitative detection of Adenovirus (F40/41) RNA.
RevoDx Astrovirus qPCR Kit
Astroviruses are one of the leading causes of pediatric gastroenteritis worldwide and are clinically importantly pathogens in the elderly and immunocompromised populations.
Intended Use
RevoDx Astrovirus qPCR Kit is a real-time PCR test intended for the qualitative detection of Astrovirus RNA.
RevoDx Monkeypox Virus qPCR Kit
There is currently a multi-country outbreak of monkeypox in several regions of the world, the full extent and impact of which remains unclear. Monkeypox starts with fever, then general body aches, malaise, and muscle aches. with the first symptoms are similar to influenza. Those usually precede the development of a rash. It starts as macules, which are flat lesions. Then it forms a firm nodule. From there, it becomes a blister, then a pustule (a blister containing pus) and then it scabs over. Monkeypox is transmitted through close person-to-person contact with lesions, body fluids and respiratory droplets, and through contaminated materials. Monkeypox virus is an enveloped double-stranded DNA virus that belongs to the Orthopoxvirus genus of the Poxviridae family. Monkeypox is a linear DNA genome of ≈197 kb and contains ≈190 nonoverlapping ORFs >180 nt long. Like all orthopoxviruses, the central coding region sequence (CRS) at Monkeypox virus nucleotide positions ≈56000–120000 is highly conserved and flanked by variable ends that contain inverted terminal repeats (ITRs).
Intended Use
RevoDx Monkeypox Virus qPCR Kit is a real-time PCR test intended for the qualitative detection of Monkeypox Virus DNA.
Features
- Ready-to-use kit
- Compatible with most real-time PCR detection systems with the channels FAM, HEX, ROX, CY5
- Human RNase P as an internal control
- No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.
Ordering Information