RevoDx Sepsis Pathogen Detection Kit

Sepsis is a syndrome that is followed by organ failure due to an uncontrolled inflammatory response of the host against infection. Early diagnosis of bloodstream infections, including those caused by bacteria and fungi, is central to reducing drastic infection-related consequences, such as significant risks of morbidity and mortality. The survival rate of septic patients mainly depends on a rapid and reliable diagnosis, since in the case of severe sepsis there is an average 7.6% decrease in survival rate per hour from the onset of hypotension without effective antimicrobial treatment. Conventional method, blood culture, has some disadvantages with regard to the desired rapidity and sensitivity. Furthermore, it is influenced by various factors and can reduce the chance of a positive result. During severe infection, empirical antibiotic therapy is inappropriate in roughly one-third of cases, and this substantially increases mortality and hospital length of stay. Furthermore, delays in optimal antimicrobial therapy may drive poor health care quality as well as increase antimicrobial resistance. As Idil Biotech, we provide a solution to all the difficulties experienced in sepsis with the RevoDx Sepsis Pathogen Detection Kit.

 

Intended Use

RevoDx Sepsis Pathogen Detection Kit is a real-time PCR test intended for the qualitative detection and identification of nucleic acids from the specific pathogens of bloodstream infection. RevoDx Sepsis Pathogen Detection Kit is performed directly on whole blood samples or on blood culture samples detected as positive.

The following pathogens and drug resistance genes are detected by RevoDx Sepsis Pathogen Detection Kit: 

The following pathogens and drug resistance genes are detected by RevoDx Sepsis Pathogen Detection Kit: 

 

Gram Negative Bacteria

  • Pseudomonas aeruginosa 

  • Klebsiella pneumonia

  • Enterobacter cloacae

  • Escherichia coli

  • Acinetobacter baumannii

  • Stenotrophomonas maltophilia

  • Neisseria meningitidis

  • Haemophilus influenzae

Gram Positive Bacteria

  • Staphyloccocus aureus

  • Staphyloccocus spp

  • Enterococcus faecalis

  • Enterococcus faecium

  • Streptococcus pneumoniae

  • Streptococcus pneumoniae

  • Streptococcus agalactiae

  • Listeria monocytogenes

Fungi

  • Candida albicans

  • Candida spp

  • Cryptococcus neoformans/gattii

Drug Resistance Genes

  • Carbapenem resistance (blaNDM, blaKPC, blaIMP, blaOXA48, blaVIM)

  • Methicillin resistance (mecA/mecC)

  • Vancomycin resistance (vanA/vanB)

  • Colistin resistance

  • Extended Spectrum Beta-Lactamases (ESBL) Genes (CTX-M, TEM, SHV)

 

Features

  • Multiple targets 8 tubes
  • Ready-to-use kit either in tube format or 8-Well Strips format
  • Human RNase P as an internal control
  • CE-IVD marked
  • Assay duration: 45 mins
  • The Limit of Detection (LoD) value is 200 CFU/mL
  • Diagnostic specificity is ≥ 99 %
  • No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.

Ordering Information

Product Name

Package

Cat. No.

RevoDx Sepsis Pathogen Detection Kit

48 tests

IP202201-48

RevoDx Sepsis Pathogen Detection Kit (ready-to-use kit in 8-well strips)

48 tests

IP202201-48s

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