RevoDx HLA-B27 Direct qPCR Kit
HLA-B27 refers to a specific human leukocyte antigen (HLA) protein, a key component of the immune system. It plays a role in helping the immune system distinguish between self and non-self cells. The presence of HLA-B27 has been strongly associated with certain autoimmune diseases, particularly ankylosing spondylitis (AS) and other spondyloarthropathies. Detection and diagnosis of HLA-B27 are important in assessing the risk and prognosis of these diseases. PCR diagnosis of HLA-B27 is a sensitive and specific method for detecting the presence of this allele, and it plays a crucial role in the diagnosis and management of diseases such as ankylosing spondylitis and other spondyloarthropathies.
Intended Use
RevoDx HLA-B27 Dirrect qPCR Kit is a real-time PCR test intended for the qualitative detection of HLA-B27 alleles.
Features
- Ready-to-use kit
- House keeping gene as an internal control
- CE-IVD marked
- Extraction free
- Whole blood as a specimens
- Assay duration: 45 mins
- Diagnostic specificity is ≥ 99 %
- No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.