RevoDx Carbapenem resistance qPCR Kit
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. Carbapenems are a powerful group of broad-spectrum beta-lactam (penicillin-related) antibiotics. In many cases, these are our last effective defense against infections caused by multi-resistant bacteria, such as some strains of Klebsiella pneumoniae and Escherichia coli. Resistance to carbapenems has emerged and is beginning to spread. New antibiotics need to be developed to counter bacteria with this type of resistance. Hospitals need good infection control to prevent their spread. .
Intended Use
RevoDx Carbapenem resistance qPCR Kit is a real-time PCR test intended for the qualitative detection of blaNDM, blaKPC, blaIMP, blaOXA48 and blaVIM genes in single tube in which human RNase P is simultaneously detected.
Features
- Ready-to-use kit
- Compatible with most real-time PCR detection systems with the channels FAM and HEX
- Human RNase P as an internal control
- The Limit of Detection (LoD) value is 88 copies/mL
- No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.
- CE-IVD marked