RevoDx

Meningitis/Encephalitis Pathogen Plus Detection Kit

Infections of the nervous system are potentially life-threatening and are caused by pathogens, such as bacteria, viruses, and fungi. Prompt recognition and treatment of a central nervous system (CNS) infection is crucial for patient survival, as these infections have a high morbidity and mortality. CNS infections include meningitis, encephalitis, and brain abscesses. Early recognition of causative pathogens is critical for the appropriate management of central nervous system infection and improved outcomes. Delays in the diagnosis and treatment of bacterial meningitis and HSV meningoencephalitis are associated with morbidity and mortality. Conversely, unnecessary antimicrobial treatment and hospitalization can be associated with the selection of antimicrobial resistance, dysbiosis, and increased health care costs.

 

Intended Use

RevoDx Meningitis/Encephalitis Pathogen PLUS Detection Kit is a real-time PCR test intended for the qualitative detection and identification of nucleic acids of the specific bacterial, viral, and fungal pathogens from cerebrospinal fluid (CSF) specimens

The following bacterial, viral, and fungal pathogens are detected by RevoDx Meningitis/Encephalitis Pathogen PLUS Detection Kit: 

Bacteria

  • Streptococcus agalactiae

  • Streptococcus pneumoniae

  • Neisseria meningitidis 

  • Haemophilus influenzae 

  • Listeria monocytogenes 

  • Escherichia coli K1

  • Mycobacterium tuberculosis

  • Mycoplasma pneumoniae

Viruses

  • Cytomegalovirus (CMV)

  • Epstein-Barr Virus (EBV) 

  • Varicella-zoster virus (VZV) 

  • Human parechovirus (HPeV) 

  • Enterovirus  

  • Herpes simplex virus type 1 (HSV1) 

  • Herpes simplex virus type 2 (HSV2) 

  • Human herpes virus 6 (HHV 6) 

  • Human herpes virus 7 (HHV 7) 

  • Mumps virus

  • Adenovirus

  • Parvovirus B19

Fungi

  • Cryptococcus neoformans/gattii

 

Features

  • Multiple targets (21 targets in 7 tubes)
  • Ready-to-use kit either in tube format or 8-Well Strips format
  • Human RNase P as an internal control
  • Assay duration: 60 mins
  • Diagnostic specificity is ≥ 99 %
  • No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.

Ordering Information

Product Name

Package

Cat. No.

RevoDx Meningitis/Encephalitis Pathogen PLUS Detection Kit

48 tests

IP202426-48

RevoDx Meningitis/Encephalitis Pathogen PLUS Detection Kit (ready-to-use kit in 8-well strips)

48 tests

IP202426-48s

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